Kabalin NJ, Hodge KK, McNeal JE, Freiha FS, Stamey TA (1989) Identification of residual cancer in the prostate following radiation therapy: role of transrectal ultrasound guided biopsy and prostate specific antigen. Hochstetler JA, Kreder KJ, Brown CK, Loening SA (1995) Survival of patients with localized prostate cancer treated with percutaneous transperineal placement of radioactive gold seeds: stages A2, B and C. Herr HW, Whitemore WF (1982) Significance of prostatic biopsies after radiation therapy for carcinoma of the prostate. Hanks GE (1994) Treatment of early stage prostate cancer: radiotherapy. Clinical rationale and results in deep seated tumors. N Engl J Med 331: 996–1004įeldmann HJ, Seegenschmiedt MH, Molls M (1995) Hyperthermia-its actual role in radiation oncology. Cancer 71: 939–952Ĭatalona WJ (1994) Management of cancer of the prostate. Cancer 60: 521–525īagshaw MA, Kalpan ID, Cox RC (1992) Radiation therapy for localized disease. Radiology 85: 121–129īagshaw MA, Ray GR, Cox RS (1987) Selecting initial therapy for prostate cancer. J Urol 149: 326–329īagshaw MA, Kaplan HS, Sageimann RH (1965) Linear accelerator supervoltage radiotherapy: carcinoma of the prostate. We therefore conclude that iridium 192 high-dose-rate brachytherapy is a useful alternative in the treatment of localized prostate cancer in patients who are not eligible for radical prostatectomy.Īdolfsson J (1993) Deferred treatment of low grade stage T3 prostate cancer without distant metastasis. Local tumor control was achieved by means of prostatic biopsy at 18 months after therapy and determination of prostate-specific antigen (PSA) values in bout 70% of the patients after a mean follow-up period of more than 6 years (16–130 months), 80% of the patients show either no evidence of disease or stable disease. Since 1984 we have treated 40 patients with this protocol. This treatment is repeated once after 7 days 2 weeks later, 18 × 2-Gy external beam radiation (small-field prostate) is added as percutaneous dose saturation. A 9-Gy prostate dose is applied followed by 30 min of hyperthermia (since 1991). Using regional anesthesia, five to seven hollow needles are placed within the prostate by perineal puncture under ultrasound guidance. ![]() We report on a novel protocol involving iridium 192 high-dose-rate brachytherapy and follow-up of up to 130 months in patients with prostatic carcinoma.
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